Publications | Wooley Research Group

2026

Andras, A. M.; Fatima, N.; Kuo, K.-H. M.; Tran, D. K.; Darensbourg, D. J.; Wooley, K. L. “Investigation of Sulfur-related Influences on the Construction and Ring Opening of a Six-membered Cyclic Xanthate Derived from d-Thymidine and CS₂”, J. Am. Chem. Soc., 2026, DOI: 10.1021/jacs.6c15290.

Published by the American Chemical Society on October 5, 2026. This study investigates sulfur-containing cyclic monomers derived from D-thymidine and carbon disulfide, showing how monomer configuration and polymerization temperature control ring opening and the backbone connectivity of synthetic nucleic acid analogs.

Andras et al., Journal of the American Chemical Society (2026), doi:10.1021/jacs.6c15290, CC BY 4.0. Graphical abstract extracted from the article.
Li, S.-G.; Gillett, L. P.; Kuo, K.-H. M.; Lim, S.-M.; Mohanty, K. T.; Kuo, Y.-T.; Wang, Q.; Easley, A. D.; Lutkenhaus, J. L.; Wooley, K. L. “Mussel-Inspired Catechol-Functionalized Redox-Active Polypeptides for Energy Applications”, Biomacromolecules, 2026, DOI: 10.1021/acs.biomac.6c00104.

Published by the American Chemical Society on April 13, 2026. Mussel-inspired, catechol-functionalized polypeptides were synthesized from natural feedstocks and investigated as redox-active organic electrode materials, combining electrochemical performance with sustainability and cytocompatibility.

Li, Gillett, Kuo et al., Biomacromolecules (2026), CC BY 4.0.

2025

Getzler, Y. D. Y. L.; Davidson, E. C.; Hartwig J. F.; Wooley, K. L.; Romain, C.; Kalčíková, G.; Plajer, A. J.; Wurm, F. R.; Gao, L.; Unni, A. B. “Breakthroughs toward sustainable polymers”, One Earth, 2025, 8(11), 101522, DOI: 10.1016/j.oneear.2025.101522.

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Li, S. G.; Mohanty, K. T.; Easley, A. D.; Rezenom, Y. H.; Lim, S.-M.; Gillett, L. P.; Naquin, S. D.; Tran, D. K.; Nguyen, T. P.; Lutkenhaus, J. L.; Wooley, K. L. “A bioinspired and degradable riboflavin-containing polypeptide as a sustainable material for energy storage”, PNAS, 2025, 122(26), e2509325122, DOI: 10.1073/pnas.2509325122.

Li et al., PNAS (2025), CC BY-NC-ND 4.0.
Smolen, J. A.; Moore, G. E.; Perez, N. D.; Wooley, K. L. “Adaptable microplastic classification using similarity learning on µFTIR spectra collected from µFTIR focal plane array imaging”, PNAS, 2025, 122(42), e2509745122, DOI: 10.1073/pnas.2509745122.

Graphical preview supplied with the original Wooley Research Group publication listing; no external reuse license is implied.
Hsieh, C.-M.; Sengoden, M.; Lim, S.-M.; Smolen, J. A.; Ahmed, N.; Wooley, K. L.; Darensbourg D. J.; Pentzer, E. B.; Wei, P. “Bioderived, 3D-Printable, and Biocompatible Polycarbonate/Hydroxyapatite Composite Scaffolds”, ACS Sustainable Chem. Eng., 2025, DOI: 10.1021/acssuschemeng.5c06987.

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2024

Easley, A. D.; Li, C.-H.; Li, S.-G.; Nguyen, T. P.; Kuo, K.-H. M.; Wooley, K. L.; Tabor, D. P.; Lutkenhaus, J. “Electron Transport Kinetics for Viologen-containing Polypeptides with Varying Side Group Linker Spacing”, J. Mater. Chem. A, 2024, 12, 31871-31882, DOI: 10.1039/d4ta06766e.

Graphical preview supplied with the original Wooley Research Group publication listing; no external reuse license is implied.

2023

Tran, D. K.; Braaksma, A. N.; Andras, A. M.; Boopathi, S. K.; Darensbourg, D. J.; Wooley, K. L. “Structural metamorphoses of d-xylose oxetane- and carbonyl sulfide-based polymers in-situ during ring-opening copolymerizations”, J. Am. Chem. Soc., 2023, 145(33), 18560–18567, DOI: 10.1021/jacs.3c05529.
Shen, Y.; Leng, M.; Yang, Y.; Boopathi, S. K.; Sun, G.; Wooley, K. L. “Elucidation of substantial differences in ring-opening polymerization outcomes from subtle variation of glucose carbonate-based monomer substitution patterns and substituent types”, J. Am. Chem. Soc., 2023, 145(28), 15405-15413, DOI: 10.1021/jacs.3c03339.
Gheisari, R.; Vazquez, M.; Tsigkis, V.; Erdemir, A.; Wooley, K. L.; Polycarpou, A. A. “Microencapsulated paraffin as a tribological additive for advanced polymeric coatings”, Friction, 2023, 11(10), 1939-1952, DOI: 10.1007/s40544-022-0733-3.
Pang, C.; Wang, H.; Zhang, F.; Patel, A.; Lee, H. P.; Wooley, K. L. “Glucose-derived superabsorbent hydrogel materials based on mechanically-interlocked slide-ring and triblock copolymer topologies”, J. Polym. Sci., 2023, 61, 937–950, DOI: 10.1002/pol.20220639.
Su, L.; Dalby, K. S.; Luehmann, H.; Elkassih, S. A.; Cho, S.; He, X.; Detering, L.; Lin. Y.-N.; Kang, N.; Moore, D. A.; Laforest, R.; Sun, G; Liu, Y.; Wooley, K. L. “Ultrasmall, Elementary and Highly Translational Nanoparticle X-ray Contrast Media from Amphiphilic Iodinated Statistical Copolymers”, Acta Pharm. Sin. B., 2023, 13, 1660-1670, DOI: 10.1016/j.apsb.2022.09.009.

2022

Smolen, J. A.; Wooley, K. L. “Fluorescence Lifetime Image Microscopy Prediction with Convolutional Neural Networks for Cell Detection and Classification in Tissues”, PNAS Nexus, 2022, DOI: 10.1093/pnasnexus/pgac235.
Eissa, R. A.; Saafan, H. A.; Ali, A. E.; Ibrahim, K. M.; Eissa, N. G.; Hamad, M. A.; Pang, C.; Guo, H.; Gao, H.; Elsabahy, M.; Wooley, K. L. “Design of Nanoconstructs that Exhibit Enhanced Hemostatic Efficiency and Bioabsorbability”, Nanoscale, 2022, 14, 10738-10749, DOI: 10.1039/D2NR02043B.
Liang, Z.; Nguyen, T. P.; Attanayake, N. H.; Easley, A. D.; Lutkenhaus, J. L.; Wooley, K. L.; Odom, S. A. “Metal-free Polypeptide Redox Flow Batteries”, Materials Advances, 2022, 3, 6558-6565, DOI: 10.1039/D2MA00498D.
Singh, M.; Dong, M.; Wu, W.; Nejat, R.; Tran, D. K.; Pradhan, N.; Raghavan, D.; Douglas, J. F.; Wooley, K. L.; Karim, A. “Enhanced Dielectric Strength and Capacitive Energy Density in Cyclic Polystyrene Films”, ACS Polymers Au, 2022, ASAP, DOI: 10.1021/acspolymersau.2c00014.
Kang, N.; Cho, S.; Leonhardt, E. E.; Liu, C.; Verkhoturov, S. V.; Woodward, W. H.; Eller, M. J.; Yuan, T.; Fitzgibbons, T. C.; Borguet, Y.; Jahnke, A. A.; Sokolov, A. N.; McIntire, T.; Reinhardt, C.; Fang, L.; Schweikert, E. A.; Spencer, L. P.; Sun, G.; Trefonas, P.; Wooley, K. L. “Topological Design of Highly Anisotropic Aligned Hole Transporting Molecular Bottlebrushes for Solution-processed OLEDs”, JACS, 2022, 144(18), 8084-8095, DOI: 10.1021/jacs.2c00420.
Shen, Y.; Yang, X.; Song, Y.; Tran, D. K.; Wang, H.; Wilson, J.; Dong, M.; Vazquez, M.; Sun, G.; Wooley, K. L. “Complexities of Regioselective Ring-opening Directionality vs. Transcarbonylation-driven Structural Metamorphosis During Organocatalytic Polymerizations of Five-membered Cyclic Carbonate Glucose Monomers”, JACS Au, 2022, 2(2), 515-521, DOI: 10.1021/jacsau.1c00545.

2021

Tran, D. K.; Rashad, A. Z.; Darensbourg, D. J.; Wooley, K. L. “Sustainable Synthesis of CO2-derived Polycarbonates from D-Xylose”, Polym. Chem., 2021, 12, 5271-5278, DOI: 10.1039/D1PY00784J. Part of the “Sustainable Polymers online themed collection” and selected as a HOT Polymer Chemistry article.
Elsabahy, M.; Song, Y.; Eissa, N. G.; Khan, S.; Hamad, M. A.; Wooley, K. L. “Morphologic design of sugar-based polymer nanoparticles for delivery of antidiabetic peptides”, J. Control. Release, 2021, 334, 1-10, DOI: 10.1016/j.jconrel.2021.04.006.
Song, Y.; Elsabahy, M.; Collins, C. A.; Khan, S.; Li, R.; Hreha, T. N.; Shen, Y.; Lin, Y.-N.; Letteri, R. A.; Su, L.; Dong, M.; Zhang, F.; Hunstad, D. A.; Wooley, K. L. “Morphologic Design of Silver-Bearing Sugar-Based Polymer Nanoparticles for Uroepithelial Cell Binding and Antimicrobial Delivery”, Nano Lett., 2021, 21, 4990-4998, DOI: 10.1021/acs.nanolett.1c00776.
Nguyen, T. P.; Easley, A. D.; Kang, N.; Khan, S.; Lim, S.-M.; Rezenom, Y. H.; Wang, S.; Tran, D. K.; Fan, J.; Letteri, R. A.; He, X.; Su, L.; Yu, C.-H.; Lutkenhaus, J. L.; Wooley, K. L. “Polypeptide Organic Radical Batteries”, Nature, 2021, 593, 61-66, DOI: 10.1038/s41586-021-03399-1.
Elsabahy, M.; Wooley, K. L.; Hendricksen, A.; Oh, K. “Multiple Analyte Profiling (MAP) Index as a Powerful Diagnostic and Therapeutic Monitoring Tool”, Methods, 2021, 190, 26-32, DOI: 10.1016/j.ymeth.2020.03.006.

2020

Pectol, D. C.; Khan, S.; Elsabahy, M.; Wooley, K. L.; Lim, S.-M.; Darensbourg, M. Y. “Effects of Glutathione and Histidine on NO Release from a Dimeric Dinitrosyl Iron Complex (DNIC)”, Inorg. Chem., 2020, 59(23), 16998-17008, DOI: 10.1021/acs.inorgchem.0c02196.
Song, Y.; Yang, X.; Shen, Y.; Dong, M.; Lin, Y.-N.; Hall, M. B.; Wooley, K. L. “Invoking side-chain functionality for the mediation of regioselectivity during ring-opening polymerization of glucose carbonates”, J. Am. Chem. Soc., 2020, 142(40), 16974-16981, DOI: 10.1021/jacs.0c05610.
Lee, J. Y.; Song, Y.; Wessels, M. G.; Jayaraman, A.; Wooley, K. L.; Pochan, D. J. "Hierarchical Self- assembly of Poly(D-glucose carbonate) Amphiphilic Block Copolymers in Mixed Solvents", Macromolecules., 2020, 53(9), 6563-6571, DOI: 10.1021/acs.macromol.0c01575.
Lin, Y.-N.; Khan, S.; Song, Y.; Dong, M.; Shen, Y.; Tran, D. K.; Pang, C.; Zhang, F.; Wooley, K. L. “A Tale of Drug-Carrier Optimization: Controlling stimuli sensitivity via nanoparticle hydrophobicity through drug loading”, Nano Lett., 2020, 20(19), 8581-8591, DOI: 10.1021/acs.nanolett.0c02319.
Lin, Y.-N.; Elsabahy, M.; Khan, S.; Zhang, F.; Song, Y.; Dong, M.; Li, R.; Smolen, J. A.; Letteri, R. A.; Su, L.; Wooley, K. L. “Erythrocyte membrane-camouflaged nanocarriers with tunable paclitaxel release kinetics via macromolecular stereocomplexation”, ACS Mater. Lett., 2020, 2(6), 596-601, DOI: 10.1021/acsmaterialslett.0c00044.
Dong, M.; Song, Y.; Wang, H.; Su, L.; Shen, Y.; Tran, D. K.; Letteri, R. A.; Flores, J. A.; Lin, Y.-N.; Li, J.; Wooley, K. L. “Degradable Sugar-based Magnetic Hybrid Nanoparticles for Recovery of Crude Oil from Aqueous Environments”, Polym. Chem., 2020, Advance Article, DOI: 10.1039/D0PY00029A. [Special Issue on the topic of “Plastics Circular Economy”].
Zhang, Q.; Wooley, K. L. “Investigation of Segmental Reorganization within Amphiphilic Block Polymer Nanoparticles Derived from Shell Crosslinked Micelle Templates: SCK inversion”, J. Polym. Sci., 2020, 58(1), 204-214, DOI: 10.1002/pol.20190089. [A special issue in tribute to Krzysztof Matyjaszewski on the occasion of his 70th birthday.].

2019

Li, R.; Wang, H.; Song, Y.; Lin, Y.-N.; Dong, M.; Khan, S.; Zhang, S.; Fan, J.; Zhang, F.; Su, L.; Wooley, K. L. “In situ production of Ag/polymer asymmetric nanoparticles via a powerful light-driven technique”, J. Am. Chem. Soc., 2019, 141(50), 19542-19545, DOI: 10.1021/jacs.9b10205.
Heo, G. S.; Cho, S.; Wooley, K. L. “Preparation of Degradable Polymeric Nanoparticles with Various Sizes and Surface Charges from Polycarbonate Block Copolymers”, Macromol. Res., 2019, 27(11), 1173-1178, DOI: 10.1007/s13233-020-8044-x.
Ron, C. A.; Dong, M.; Wooley, K. L.; Johnson, W. P. “Theory-Guided Targeted Delivery of Nanoparticles in Advective Environmental Porous Media”, Environ. Sci. Technol. Lett., 2019, 6(10), 617-623, DOI: 10.1021/acs.estlett.9b00474.
Beltran-Villegas, D. J.; Wessels, M. G.; Lee, J. Y.; Song, Y.; Wooley, K. L.; Pochan, D. J.; Jayaraman, A. “Computational Reverse-Engineering Analysis for Scattering Experiments (CREASE) on Amphiphilic Block Polymer Solutions”, J. Am. Chem. Soc., 2019, 141(37), 14916-14930, DOI: 10.1021/jacs.9b08028.
Heo, G. S.; Zhao, Y.; Sultan, D.; Zhang, X.; Detering, L.; Luehmann, H. P.; Zhang, X.; Li, R.; Choksi, A.; Sharp, S.; Levingston, S.; Primeau, T.; Reichert, D. E.; Sun, G.; Razani, B.; Li, S.; Weilbaecher, K. N.; Dehdashti, F.; Wooley, K. L.; Liu, Y. “Assessment of Copper Nanoclusters for Accurate In vivo Tumor Imaging and Potential for Translation”, ACS Appl. Mater. Interfaces, 2019, 11(22), 19669-19678, DOI: 10.1021/acsami.8b22752.
Pectol, D. C.; Chupik, R. B.; Khan, S.; Elsabahy, M.; Wooley, K. L.; Darensbourg, M. Y.; Lim, S.-M. “Towards the Optimization of Dinitrosyl Iron Complexes as NO Delivery Agents to Smooth Muscle Cells”, Mol. Pharmaceutics, 2019, 16(7), 3178-3187, DOI: 10.1021/acs.molpharmaceut.9b00389.
Leonhardt, E. E.; Kang, N.; Hamad, M. A.; Wooley, K. L.; Elsabahy, M. “Absorbable Hemostatic Hydrogels Comprising Composites of Sacrificial Templates and Honeycomb-like Nanofibrous Mats of Chitosan”, Nature Commun., 2019, 10:2307, 1-9, DOI: 10.1038/s41467-019-10290-1.
Dong, M.; Wessels, M. G.; Lee, J. Y.; Su, L.; Wang, H.; Letteri, R. A.; Song, Y.; Lin, Y.-N.; Chen, Y.; Li, R.; Pochan, D. J.; Jayaraman, A.; Wooley, K. L. “Experiments and Simulations of Complex Sugar‑based Coil‑brush Block Polymer Nanoassemblies in Aqueous Solution”, ACS Nano, 2019, 13(5), 5147-5162, DOI: 10.1021/acsnano.8b08811.
Elsabahy, M.; Wooley, K. L.; Hendricksen, A.; Oh, K. “Multiplexing Techniques for Measurement of the Immunomodulatory Effects of Particulate Materials: Precautions when testing micro- and nano-particles”, Methods, 2019, 158, 81-85, DOI: 10.1016/j.ymeth.2019.01.006.
Li, R.; Elsabahy, M.; Song, Y.; Wang, H.; Su, L.; Letteri, R.A.; Khan, S.; Heo, G. S.; Sun, G.; Liu, Y.; Wooley, K. L. “Functional, degradable zwitterionic polyphosphoesters as biocompatible coating materials for metal nanostructures”, Langmuir, 2019, 35(5), 1503-1512, DOI: 10.1021/acs.langmuir.8b02033 [A special issue on the topic of “Zwitterionic Interfaces: Concepts and emerging applications”].
Osumi, S.; Felder, S. E.; Wang, H.; Lin, Y.-N.; Dong, M.; Wooley, K. L. “Construction of nanostructures in aqueous solution from amphiphilic glucose-derived polycarbonates”, J. Polym. Sci., Part A: Polym. Chem., 2019, 57(3), 432-440, DOI: 10.1002/pola.29229 [A special issue in honor of Professor Mitsuo Sawamoto, in recognition of his outstanding achievements and retirement from 40 years of exceptional service to Kyoto University].
Wacker, K. T.; Weems, A. C.; Lim, S.-M.; Khan, S.; Felder, S. E.; Dove, A. P.; Wooley, K. L. “Harnessing the Chemical Diversity of the Natural Product Magnolol for the Synthesis of Renewable, Degradable Neolignan Thermosets with Tunable Thermomechanical Characteristics and Antioxidant Activity”, Biomacromolecules, 2019, 20(1), 109-117, DOI: 10.1021/acs.biomac.8b00771 [A special issue in coordination with the 2018 Bordeaux Polymer Conference].

2018

Song, Y.; Ji, X.; Dong, M.; Li, R.; Lin, Y.-N.; Wang, H.; Wooley, K. L. “Advancing the Development of Highly-functionalizable Glucose‑based Polycarbonates by Tuning of the Glass Transition Temperature”, J. Am. Chem. Soc., 2018, 140(47), 16053-16057, DOI: 10.1021/jacs.8b10675.
Lin, Y.-N.; Su, L.; Smolen, J.; Li, R.; Song, Y.; Wang, H.; Dong, M.; Wooley, K. L. “Co-assembly of sugar-based amphiphilic block polymers to achieve nanoparticles with tunable morphology, size, surface charge, and acid-responsive behavior”, Mater. Chem. Front., 2018, 2(12), 2230-2238, DOI: 10.1039/C8QM00353J.
Leonhardt, E. E.; Meador, M. A. B.; Wooley, K. L. “β-Cyclodextrin-derived Monolithic, Hierarchically Porous Polyimides Designed for Versatile Molecular Separation Applications”, Chem. Mater., 2018, 30(18), 6226-6230, DOI: 10.1021/acs.chemmater.8b02843.
Wang, H.; Dong, M.; Khan, S.; Su, L.; Li, R.; Song, Y.; Lin, Y.-N.; Kang, N.; Komatsu, C. H.; Elsabahy, M.; Wooley, K. L. "Acid-triggered polymer backbone degradation and disassembly to achieve release of camptothecin from functional polyphosphoramidate nanoparticles" ACS Macro Lett., 2018, 7, 783-788, DOI: 10.1021/acsmacrolett.8b00377.
Elsabahy, M.; Wooley, K. L. "Reassessment of Nanomaterials Immunotoxicity", Nano Today, 2018, 20, 10-12, DOI: 10.1016/j.nantod.2018.01.002.
Cho, S.; Heo, G. S.; Khan, S.; Huang, J.; Hunstad, D. A.; Elsabahy, M.; Wooley, K. L. "A Vinyl Ether-Functional Polycarbonate as a Template for Multiple Post-polymerization Modifications" Macromolecules, 2018, 51(9), 3233-3242, DOI: 10.1021/acs.macromol.8b00047.
Shah, P. N.; Shah, K. N.; Smolen, J. A.; Tagaev, J. A.; Torrealba, J.; Zhou, L.; Zhang, S.; Zhang, F.; Wagers, P. O.; Panzner, M. J.; Youngs, W. J.; Wooley, K. L.; Cannon, C. L. "A novel in vitro metric predicts in vivo efficacy of inhaled silver-based antimicrobials in a murine Pseudomonas aeruginosa pneumonia model" Sci. Rep., 2018, 8, 6376, DOI: 10.1038/s41598-018-24200-w.
Borguet, Y. P.; Kahn, S.; Noel, A.; Gunsten, S. P.; Brody, S. L.; Elsabahy, M.; Wooley, K. L. "Development of fully degradable phosphonium-functionalized amphiphilic diblock copolymers for nucleic acids delivery", Biomacromolecules, 2018, 19 (4), 1212-1222, DOI: 10.1021/acs.biomac.8b00069.
Felder, S. E.; Redding, M. J.; Noel, A.; Grayson, S. M.; Wooley, K. L. "Organocatalyzed ROP of a Glucopyranoside Derived Five-Membered Cyclic Carbonate", Macromolecules, 2018, 51, 1787-1797, DOI: 10.1021/acs.macromol.7b01785.
Su, L.; Li, R.; Khan, S.; Clanton, R.; Zhang, F.; Lin, Y.-N.; Song, Y.; Wang, H.; Fan, J.; Hernandez, S.; Butters, A. S.; Akabani, G.; MacLoughlin, R.; Smolen, J.; Wooley, K. L. "Chemical Design of Both a Glutathione-Sensitive Dimeric Drug Guest and a Glucose-Derived Nanocarrier Host to Achieve Enhanced Osteosarcoma Lung Metastatic Anticancer Selectivity", J. Am. Chem. Soc., 2018, 140, 1438-1446, DOI: 10.1021/jacs.7b11462.
Tsao, Y.-Y. T.; Smith, T. H.; Wooley, K. L. "Regioisomeric Preference in Ring-Opening Polymerization of 3’,5’-Cyclic Phosphoesters of Functional Thymidine DNA Analogues", ACS Macro Lett., 2018, 7, 153-158, DOI: 10.1021/acsmacrolett.7b00858.

2017

Song, Y.; Chen, Y.; Su, L.; Li, R.; Letteri, R. A.; Wooley, K. L. "Crystallization-driven Assembly of Fully Degradable, Natural Product-based Poly(L-lactide)-block-poly(α-D-glucose carbonate)s in Aqueous Solution", Polymer, 2017, 122, 270-279, DOI: 10.1016/j.polymer.2017.06.065 [A virtual special issue on “Advanced Polymer Synthesis for Functional Nanostructures” in honor of Axel H. E. Müller’s 70th birthday on May 8, 2017].
Lonnecker, A. T.; Lim, Y. H.; Wooley, K. L. "A Functional Polycarbonate of a D-Glucal-Derived Bicyclic Carbonate via Organocatalytic Ring-Opening Polymerization", ACS Macro Lett., 2017, 6, 748-753, DOI: 10.1021/acsmacrolett.7b00362.
Fan, J.; Li, R.; Wang, H.; He, X.; Nguyen, T. P.; Letteri, R. A.; Zou, J.; Wooley, K. L. "Multi-responsive polypeptide hydrogels derived from N-carboxyanhydride terpolymerizations for delivery of nonsteroidal anti-inflammatory drugs (NSAIDs)", Org. Biomol. Chem., 2017, 15, 5145-5154, DOI: 10.1039/C7OB00931C.
Tsao, Y.-Y. T.; Wooley, K. L. "Synthetic, Functional Thymidine-derived Polydeoxyribonucleotide-analogs from a 6-Membered Cyclic Phosphoester", J. Am. Chem. Soc., 2017, 139, 5467-5473, DOI: 10.1021/jacs.7b01116. PMCID: PMC5451148.
Kristufek, S. L.; Wacker, K. T.; Tsao, Y.-Y.; Su, L.; Wooley, K. L. "Monomer design strategies to create natural product-based polymer materials", Nat. Prod. Rev., 2017, 34, 433-459, DOI: 10.1039/C6NP00112B.
Mohamed. N. K.; Hamad, M. A.; Hafez, M. Z. E.; Wooley, K. L.; Elsabahy M. "Nanomedicine in Management of Hepatocellular Carcinoma: Challenges and Opportunities", Int. J. Cancer, 2017, 140, 1475-1484, DOI: 10.1002/ijc.30517.
Su, L.; Khan, S.; Fan, J.; Lin, Y.-N.; Wang, H.; Gustafson, T. P.; Zhang, F.; Wooley, K. L. "Functional sugar-based polymers and nanostructures comprised of degradable poly(D-glucose carbonate)s", Polym. Chem., 2017, 8, 1699-1707, DOI: 10.1039/C6PY01978A.
Wang, H.; Su, L.; Li, R.; Zhang, S.; Fan, J.; Zhang, F.; Nguyen, T. P.; Wooley, K. L. "Polyphosphoramidates that undergo acid-triggered backbone degradation", ACS Macro Lett., 2017, 6, 219-223, DOI: 10.1021/acsmacrolett.6b00966.
Elzeny, H.; Zhang, F.; Ali, E. N.; Fathi, H. A.; Zhang, S.; Li, R.; El-Mokhtar, M. A.; Hamad, M. A.; Wooley, K. L.; Elsabahy, M. "Polyphosphoester nanoparticles as biodegradable platform for delivery of multiple drugs and siRNA", Drug Des. Devel. Ther., 2017, 11, 483-496, DOI: 10.2147/DDDT.S128503.
Zhang, F.; Khan, S.; Li, R.; Smolen, J.; Zhang, S.; Zhu, G.; Su, L.; Jahnke, A.; Elsabahy, M.; Chen, X.; Wooley, K. L. "Design and development of multifunctional polyphosphoester-based nanoparticles for ultrahigh paclitaxel dual loading", Nanoscale, 2017, 9, 15773-15777, DOI: 10.1039/C7NR05935C.

2016

Zigmond, J. S.; Wooley, K. L. “Amphiphilic Crosslinked Liquid Crystalline Fluoropolymer-Poly(ethylene glycol) Coatings for Application in Challenging Conditions: Comparative study between different liquid crystalline comonomers and polymer architectures”, ACS Appl. Mater. Interfaces, DOI 10.1021/acsami.6b11112.
Flores, J. A.; Jahnke, A. A.; Cheng, Z.; Wooley, K. L. “Magnetically-active Pickering Emulsions Stabilized by Hybrid Inorganic/Organic Networks”, Soft Matter, 2016, 12(46), 9342-9354, DOI: 10.1039/C6SM01830K.
Yang, G.; Kristufek, S. L.; Link, L. A.; Wooley, K. L.; Robertson, M. L. “Thiol-ene elastomers derived from biobased phenolic acids with varying functionality”, Macromolecules, 2016, 49(20), 7737-7748, DOI: 10.1021/acs.macromol.6b01018.
Lonnecker, A. T.; Lim, Y. H.; Felder, S. E.; Besset, C. J.; Wooley, K. L. “Four Different Regioisomeric Polycarbonates Derived from One Natural Product, d-Glucose”, Macromolecules, 2016, 49(20), 7857-7867, DOI: 10.1021/acs.macromol.6b00591.
Wacker, K. T.; Kristufek, S. L.; Lim, S.-M.; Kahn, S.; Wooley, K. L. “Bio-based Polycarbonates Derived from the Neolignan Honokiol”, RSC Advances, 2016, 6(85), 81672-81679, DOI: 10.1039/C6RA19568G.
Kristufek, S. L.; Yang, G.; Link, L. A.; Rohde, B. J.; Robertson, M. L.; Wooley, K. L. “Synthesis, Characterization and Cross-linking Strategy of a Quercetin-based Epoxidized Monomer as a Naturally-Derived Replacement for BPA in Epoxy Resins”, Chem. Sus. Chem., 2016, 9(16), 2135-2142, DOI: 10.1002/cssc.201600392.
Lim, Y. H.; Tiemann, K. M.; Hunstad, D. A.; Elsabahy, M.; Wooley, K. L. “Polymeric Nanoparticles in Development for Treatment of Pulmonary Infectious Diseases”, Wiley Interdisciplinary Reviews (WIREs): Nanomed. Nanobiotechnol., 2016, 8(6), 842-871, DOI: 10.1002/wnan.1401. PMCID: PMC5035710.
Zigmond, J. S.; Pavia-Sanders, A.; Russell, J. D.; Wooley, K. L. “Dynamic Anti-icing Coatings: Complex, amphiphilic hyperbranched fluoropolymer poly(ethylene glycol) crosslinked networks with an integrated liquid crystalline comonomer”, Mater., 2016, 28(15), 5471-5479, DOI: 10.1021/acs.chemmater.6b02013.
He, X.; Fan, J.; Zou, J.; Wooley, K. L. “Reversible Photo-patterning of Soft Conductive Materials via Spatially-defined Supramolecular Assembly”, Commun., 2016, 52(54), 8455-8458, DOI: 10.1039/C6CC03579E. PMCID: PMC5043637.
Zhao, Y.; Detering, L.; Sultan, D.; Cooper, M.; You, M.; Cho, S.; Meier, S.; Luehmann, H.; Sun, G.; Rettig, M.; Dehdashti, F.; Wooley, K. L.; DiPersio, J.; Liu, Y. “Gold Nanoclusters Doped with ⁶⁴Cu for CXCR4 Positron Emission Tomography Imaging of Breast Cancer and Metastasis”, ACS Nano, 2016, 10(6), 5959-5970, DOI: 10.1021/acsnano.6b01326.
Black, K. C.; Ibricevic, A.; Gunsten, S. P.; Flores, J. A.; Gustafson, T. P.; Raymond, J. E.; Samarajeewa, S.; Shrestha, R.; Felder, S. E.; Cai, T.; Shen, Y.; Löbs, A. K.; Zhegalova, N.; Sultan, D. H.; Berezin, M.; Wooley, K. L.; Liu, Y.; Brody, S. “In vivo fate tracking of degradable nanoparticles for lung gene transfer using PET and Cerenkov imaging”, Biomaterials, 2016, 98, 53-63, DOI: 10.1016/j.biomaterials.2016.04.040. PMCID: PMC489910.
Kristufek, T. S.; Kristufek, S. L.; Link, L. A.; Weems, A. C.; Lonnecker, A. T.; Raymond, J. E.; Maitland, D. J.; Wooley, K. L. “Rapidly-cured Isosorbide Natural Product-based Cross-linked Polycarbonate Elastomers”, Chem., 2016, 7(15), 2639-2644, DOI: 10.1039/c5py01659b.
He, X.; Fan, J.; Wooley, K. L. “Stimuli-triggered Sol-Gel Transitions of Polypeptide Gels Derived from N-carboxyanhydride (NCA) Polymerizations”, Asian J., 2016, 11(4), 437–447, DOI: 10.1002/asia.201500957.
Zigmond, J. S.; Pollack, K. A.; Smedley, S.; Raymond, J. E.; Link, L. A.; Pavia-Sanders, A.; Hickner, M. A.; Wooley, K. L. “Investigation of Intricate, Amphiphilic Crosslinked Hyperbranched Fluoropolymers as Anti-icing Coatings for Extreme Environments”, Polym. Sci., Part A: Polym. Chem., 2016, 54(2), 238–244, DOI: 10.1002/pola.27800.

2015

Noel, A.; Borguet, Y. P.; Wooley, K. L. “Self-reporting Degradable Fluorescent Grafted Copolymer Micelles Derived from Biorenewable Resources”, ACS Macro Lett., 2015,4(6), 645-650, DOI: 10.1021/acsmacrolett.5b00227. PMCID: PMC4477896.
Flores, J. A.; Pavia-Sanders, A.; Chen, Y.; Pochan, D. J.; Wooley, K. L. “Recyclable Hybrid Inorganic/Organic Magnetically-active Networks for the Sequestration of Crude Oil from Aqueous Environments”, Mater., 2015, 27, 3775-3782, DOI: 10.1021/acs.chemmater.5b01523.
Zhang, F.; Zhang, S.; Pollack, S. F.; Li, R.; Gonzalez, A. M.; Fan, J.; Zou, J.; Leininger, S. E.; Pavia-Sanders, A.; Johnson, R.; Nelson, L. D.; Raymond, J. E.; Elsabahy, M.; Hughes, D. M. P.; Lenox, M. W.; Gustafson, T. P.; Wooley, K. L. “Improving Paclitaxel Delivery: In vitroand in vivo characterization of PEGylated polyphosphoester-based nanocarriers”, Am. Chem. Soc., 2015, 137, 2056-2066, DOI: 10.1021/ja512616s.
Sun, G.; Cho, S.; Yang, F.; He, X.; Pavia-Sanders, A.; Clark, C.; Raymond, J. E.; Verkhoturov, S. V.; Schweikert, E. A.; Thackeray, J. W.; Trefonas, P.; Wooley, K. L. “Advanced Photoresist Technologies by Intricate Molecular Brush Architectures: Diblock brush terpolymer-based positive-tone photoresist materials”, Polym. Sci., Part A: Polym. Chem., 2015, 53, 193-199, DOI: 10.1002/pola.27362.
Yang, F.; Cho, S.; Sun, G.; Verkhoturov, S. V.; Thackeray, J. W.; Trefonas, P.; Wooley, K. L.; Schweikert, E. A. “Nanodomain Analysis with Cluster-SIMS: Application to the characterization of macromolecular brush architecture”, Surface and Interface Analysis, 2015, 47(11), 1051-1055, DOI: 10.1002/sia.5812.
Elsabahy, M.; Heo, G. S.; Lim, S.-M.; Sun, G.; Wooley, K. L. “Polymeric Nanostructures for Imaging and Therapy”, Chem. Rev., 2015, 115, 10967-11011, DOI: 10.1021/acs.chemrev.5b00135.
Chen, Y.; Zhang, K.; Wang, X.; Zhang, F.; Zhu, J.; Mays, J. W.; Wooley, K. L.; Pochan, D. J. “Multigeometry nanoparticles: Hybrid vesicle/cylinder nanoparticles constructed with block copolymer solution assembly and kinetic control”, Macromolecules, 2015, 48(16), 5621-5631, DOI: 10.1021/acs.macromol.5b00752.
Wagers, P. O.; Tiemann, K. M.; Shelton, K. L.; Kofron, W. G.; Panzner, M. J.; Wooley, K. L.; Youngs, W. J.; Hunstad, D. A. “Imidazolium salts as small-molecule urinary bladder exfoliants in a murine model”, Antimicrobial Agents and Chemotherapy, 2015, 59(9), 5494-5502, DOI: 10.1128/AAC.00881-15.
Weems, A. C.; Raymond, J. E.; Wacker, K. T.; Gustafson, T. P.; Keller, B.; Wooley, K. L.; Maitland, D. J. “Examination of radio-opacity enhancing additives in shape memory polyurethane foams”, J. Appl. Polym. Sci., 2015, 132(33), 42054 (9 pp), DOI: 10.1002/app.42054.
Hearon, K.; Wierzbicki, M. A.; Nash, L. D.; Landsman, T. L.; Laramy, C.; Lonnecker, A. T.; Gibbons, M. C.; Ur, S.; Cardinal, K. O.; Wilson, T. S.; Wooley, K. L.; Maitland, D. J. “A Processable Shape Memory Polymer System for Biomedical Applications”, Adv. Healthcare Mater., 2015, 4, 1386-1398, DOI: 10.1002/adhm.201500156.
Aweda, T. A.; Zhang, S.; Mupanomunda, C.; Burkemper, J.; Heo, G. S.; Bandara, N.; Lin, M.; Cutler, C. S.; Cannon, C. L.; Youngs, W. J.; Wooley, K. L.; Lapi, S. E. “Investigating the pharmacokinectics and biological distribution of silver-loaded polyphosphoester-based nanoparticles using 111Ag as a radiotracer”, J. Labelled Comp Radiopharm., 2015, 58(6), 234-241, DOI: 10.1002/jlcr.3289. PMCID: PMC4457551.
Noel, A.; Borguet, Y. P.; Wooley, K. L. “Self-reporting Degradable Fluorescent Grafted Copolymer Micelles Derived from Biorenewable Resources”, ACS Macro Lett., 2015, 4(6), 645-650, DOI: 10.1021/acsmacrolett.5b00227. PMCID: PMC4477896.
Elsabahy, M.; Wooley, K. L. “Data Mining as a Guide for the Construction of Biocompatible Nanoparticles via Controlling Polymer Chemistry and Supramolecular Assembly”, Acc. Chem. Res., 2015, 48(6), 1620-1630, DOI: 10.1021/acs.accounts.5b00066. PMCID: PMC4500541.
Flores, J. A.; Pavia-Sanders, A.; Chen, Y.; Pochan, D. J.; Wooley, K. L. “Recyclable Hybrid Inorganic/Organic Magnetically-active Networks for the Sequestration of Crude Oil from Aqueous Environments”, Chem. Mater., 2015, 27, 3775-3782, DOI: 10.1021/acs.chemmater.5b01523.
Seetho, K.; Zhang, S.; Pollack, K. A.; Zou, J.; Raymond, J. E.; Wooley, K. L. “Facile Synthesis of a Phosphorylcholine-based Zwitterionic Amphiphilic Copolymer for Anti-Biofouling Coatings”, ACS Macro Lett., 2015, 4, 505-510, DOI: 10.1021/mz500818c.
Lim, Y. H.; Tiemann, K. M.; Heo, G. S.; Wagers, P. O.; Rezenom, Y. H.; Zhang, S.; Zhang, F.; Youngs, W. J.; Hunstad, D. A.; Wooley, K. L. “Preparation and in vitro Antimicrobial Activity of Silver-bearing Degradable Polymeric Nanoparticles of Polyphosphoester-block-Poly(L-lactide)”, ACS Nano, 2015, 9(2), 1995-2008, DOI: 10.1021/nn507046h.
Zhang, F.; Zhang, S.; Pollack, S. F.; Li, R.; Gonzalez, A. M.; Fan, J.; Zou, J.; Leininger, S. E.; Pavia-Sanders, A.; Johnson, R.; Nelson, L. D.; Raymond, J. E.; Elsabahy, M.; Hughes, D. M. P.; Lenox, M. W.; Gustafson, T. P.; Wooley, K. L. “Improving Paclitaxel Delivery: In vitro and in vivo characterization of PEGylated polyphosphoester-based nanocarriers”, J. Am. Chem. Soc., 2015, 137, 2056-2066, DOI: 10.1021/ja512616s.
Zhang, F.; Smolen, J. A.; Zhang, S.; Li, R.; Shah, P. N.; Cho, S.; Wang, H.; Raymond, J. E.; Cannon, C. L.; Wooley, K. L. “Degradable polyphosphoester-based silver-loaded nanoparticles as therapeutics for bacterial lung infections”, Nanoscale, 2015, 7, 2265-2270, DOI: 10.1039/c4nr07103d.
Sun, G.; Cho, S.; Yang, F.; He, X.; Pavia-Sanders, A.; Clark, C.; Raymond, J. E.; Verkhoturov, S. V.; Schweikert, E. A.; Thackeray, J. W.; Trefonas, P.; Wooley, K. L. “Advanced Photoresist Technologies by Intricate Molecular Brush Architectures: Diblock brush terpolymer-based positive-tone photoresist materials”, J. Polym. Sci., Part A: Polym. Chem., 2015, 53, 193-199, DOI: 10.1002/pola.27362.

2014

Pollack, K. A.; Imbesi, P. M.; Raymond, J. E.; Wooley, K. L. “Hyperbranched Fluoropolymer-Polydimethylsiloxane-Poly(ethylene glycol) Crosslinked Terpolymer Networks Designed for Marine and Biomedical Applications: Heterogeneous non-toxic anti-biofouling surfaces”, ACS Appl. Mater. Interfaces, 2014, 6, 19265-19274, DOI: 10.1021/am505296n.
Noel, A.; Borguet, Y. P.; Raymond, J. E.; Wooley, K. L. “Poly(ferulic acid-co-tyrosine): Effect of the regiochemistry on the photophysical and physical properties, en route to biomedical applications”, Macromolecules, 2014, 47(20), 7109-7117, DOI: 10.1021/ma5015534. PMCID: PMC4211680.
Link, L. A.; Lonnecker, A. T.; Hearon, K.; Raymond, J. E.; Maitland, D. J.; Wooley, K. L. “Photo-crosslinked Poly(thioether-co-carbonate) Networks Derived from the Natural Product Quinic Acid”, ACS Appl. Mater. Interfaces, 2014, 6, 17370-17375, DOI: 10.1021/am506087e.
He, X.; Fan, J.; Zhang, F.; Li, R.; Pollack, K. A.; Raymond, J. E.; Zou, J.; Wooley, K. L. “Multi-responsive Hydrogels Derived from the Self-assembly of Tethered Allyl-functionalized Racemic Oligopeptides”, J. Mater. Chem. B, 2014, 2(46), 8123-8130, DOI: 10.1039/C4TB00909F. PMCID: PMC4255538.
Elsabahy, M.; Wooley, K. L. “Core-shell Nanoparticles for Biomedical Applications.” Handbook of Nanobiomedical Research: Fundamentals, Applications and Recent Developments Volume 1: Materials for Nanomedicine. Vol. 3. Ed. V. Torchilin. Singapore: WorldScientificOpen, 2014. 475-517. Print.
Lim, Y. H.; Heo, G. S.; Rezenom, Y. H.; Pollack, S.; Raymond, J. E.; Elsabahy, M.; Wooley, K. L. “Development of a Vinyl Ether-functionalized Polyphosphoester as a Template for Multiple Post-polymerization Conjugation Chemistries and Study of Core Degradable Polymeric Nanoparticles”, Macromolecules, 2014, 47, 4634-4644, DOI: 10.1021/ma402480a.
Zou, J.; He, X.; Fan, J.; Raymond, J. E.; Wooley, K. L. “Supramolecularly-knitted Tethered Oligopeptide/Single-walled Carbon Nanotube Organogels”, Chem. Eur. J., 2014, 20, 8842-8847, DOI: 10.1002/chem.201403027. PMCID: PMC4139973.
Fan, J.; Li, R.; He, X.; Seetho, K.; Zou, J.; Wooley, K. L. “Construction of a versatile and functional nanoparticle platform derived from a helical diblock copolypeptide-based biomimetic polymer”, Polym. Chem., 2014, 5, 3977-3987, DOI: 10.1039/C4PY00628C. PMCID: PMC4084918.
Noel, A.; Borguet, Y. P.; Raymond, J. E.; Wooley, K. L. “Poly(carbonate-amide)s derived from bio-based resources: Poly(ferulic acid-co-tyrosine)”, Macromolecules, 2014, 47, 2974-2983, DOI: 10.1021/ma500454f. PMCID: PMC4020594.
Heo, G. S.; Cho, S.; Wooley, K. L. “Aldehyde-Functional Polycarbonates as Reactive Platforms”, Polym. Chem., 2014, 5, 3555-3558, DOI: 10.1039/c4py00456f.
Hearon, K.; Nash, L. D.; Rodriguez, J. N.; Lonnecker, A. T.; Raymond, J. E.; Wilson, T. S.; Wooley, K. L.; Maitland, D. J. “A High-Performance Recycling Solution for Polystyrene Achieved by the Synthesis of Renewable Poly(thioether) Networks Derived from D-Limonene”, Adv. Mater., 2014, 26(10), 1552-1558, DOI: 10.1002/adma.201304370. PMCID: PMC4000729.
Gustafson, T. P.; Lim, Y. H.; Flores, J. A.; Heo, G. S.; Zhang, F.; Zhang, S.; Samarajeewa, S.; Raymond, J. E.; Wooley, K. L. “Holistic assessment of covalently-labelled core-shell polymeric nanoparticles with fluorescent contrast agents towards theranostic applications”, Langmuir, 2014, 30(9), 631-641, DOI: 10.1021/la403943w. PMCID: PMC3933954.
Zou, J.; Zhang, F.; Zhang, S.; Pollack, S. F.; Elsabahy, M.; Fan, J.; Wooley, K. L. “Poly(ethylene oxide)-block-polyphosphoester-graft-paclitaxel Conjugates with Acid-labile Linkages as a pH-Sensitive and Functional Nanoscopic Platform for Paclitaxel Delivery”, Adv. Healthcare Mater., 2014, 3(3), 441-448, DOI: 10.1002/adhm.201300235. PMCID: PMC3938983.
Cho, S.; Yang, F.; Sun, G.; Eller, M. J.; Clark, C.; Schweikert, E. A.; Thackeray, J. W.; Trefonas, P.; Wooley, K. L. “Directing Self-assembly of Nanoscopic Cylindrical Diblock Brush Terpolymers into Films with Desired Spatial Orientations: Expansion of chemical composition scope”, Macromol. Rapid Commun., 2014, 35(4), 437-441, DOI: 10.1002/marc.201300845.
Fan, J.; Zou, J.; He, X.; Zhang, F.; Zhang, S.; Raymond, J. E.; Wooley, K. L. “Tunable mechano-responsive organogels by ring-opening copolymerizations of N-carboxyanhydrides”, Chem. Sci., 2014, 5, 141-150, DOI: 10.1039/c3sc52504j. PMCID: PMC3865608.
Samarajeewa, S.; Zentay, R. P.; Jhurry, N. D.; Li, A.; Seetho, K.; Zou, J.; Wooley, K. L. “Programmed Hydrolysis of Nanoassemblies by Electrostatic Interaction-mediated Enzymatic-degradation”, Chem. Commun., 2014, 50(8), 968-970, DOI: 10.1039/c3cc46013d.
Zhao, Y.; Sultan, D.; Detering, L.; Cho, S.; Sun, G.; Pierce, R.; Wooley, K. L.; Liu, Y. “Positron Emitter Alloyed Gold Nanoparticle for Cancer Imaging: Improved Radiolabel Stability and Diagnostic Accuracy”, Angew. Chem., 2014, 53, 156-159, DOI: 10.1002/anie.201308494.

2013

Trefonas, P.; Thackeray, J. W.; Sun, G.; Cho, S.; Clark, C.; Verkhoturov, S. V.; Eller, M. J.; Li, A.; Pavia-Jimenez, A.; Schweikert, E. A.; Wooley, K. L. “Bottom-up/Top-down High Resolution, High Throughput Lithography using Vertically Assembled Block Bottle Brush Polymers”, SPIE Proceedings, 2013, paper 8682-37.
Hearon, K.; Besset, C. J.; Lonnecker, A. T.; Ware, T.; Voit, W. E.; Wilson, T. S.; Wooley, K. L.; Maitland, D. J. “A Structural Approach to Establishing a Platform Chemistry for the Tunable, Bulk Electron Beam Crosslinking of Shape Memory Polymer Systems”, Macromolecules, 2013, 46(22), 8905-8916, DOI: 10.1021/ma4018372.
Elsabahy, M.; Li, A.; Sultan, D.; Liu, Y.; Wooley, K. L. “Differential immunotoxicities of poly(ethylene glycol)- vs. poly(carboxybetaine)-coated nanoparticles”, J. Controlled Release, 2013, 172(3), 641-652, DOI: 10.1016/j.jconrel.2013.09.010. PMCID: PMC3858532.
Ibricevic, A.; Gunsten, S. P.; Zhang, K.; Shrestha, R.; Liu, Y.; Sun, J. Y.; Welch, M. J.; Taylor, J. S.; Wooley, K. L.; Brody, S. L. “PEGylation of Cationic, Shell Crosslinked Knedel-like Nanoparticles Modulates Inflammation and Enhances Cellular Uptake in the Lung”, Nanomedicine: Nanotechnology, Biology and Medicine, 2013, 9(7), 912-922, DOI: 10.1016/j.nano.2013.02.006. PMCID: PMC3724762.
Trefonas, P.; Thackeray, J. W.; Sun, G.; Cho, S.; Clark, C.; Verkhoturov, S. V.; Eller, M. J.; Li, A.; Pavia-Jimenez, A.; Schweikert, E. A.; Wooley, K. L. “Bottom-up/Top-down High-resolution, High-throughput Lithography using Vertically Assembled Block Bottle Brush Polymers”, J. Micro/Nanolith. MEMS MOEMS., 2013, 12 (4), 043006 (December 16, 2013); DOI: 10.1117/1.jmm.12.4.043006.
Elsabahy, M.; Zhang, S.; Zhang, F.; Deng, Z. J.; Lim, Y. H.; Wang, H.; Parsamian, P.; Hammond, P. T.; Wooley, K. L. “Surface Charges and Shell Crosslinks Each Play Significant Roles in Mediating Degradation, Biofouling, Cytotoxicity and Immunotoxicity for Polyphosphoester-based Nanoparticles”, Scientific Reports, 2013, 3 : 3313, 1-10, DOI: 10.1038/srep03313. PMCID: PMC3837308.
Shen, Y.; Zhang, S.; Zhang, F.; Loftis, A.; Pavia-Sanders, A.; Zou, J.; Fan, J.; Taylor, J.-S. A.; Wooley, K. L. “Polyphosphoester-based cationic nanoparticles serendipitously release integral biologically-active components to serve as novel degradable inducible nitric oxide synthase inhibitors”, Adv. Mater., 2013, 25, 5609-5614, DOI: 10.1002/adma.201302842.
Pavía-Sanders, A.; Zhang, S.; Flores, J. A.; Sanders, J. E.; Raymond, J. E.; Wooley, K. L. “Robust Magnetic/Polymer Hybrid Nanoparticles Designed for Crude Oil Entrapment and Recovery in Aqueous Environments”, ACS Nano, 2013, 7(9), 7552-7561, DOI: 10.1021/nn401541e.
Zhu, J.; Zhang, S.; Zhang, K.; Wang, X.; Mays, J. W.; Wooley, K. L.; Pochan, D. J. “Disk-Cylinder and Disk-Sphere Nanoparticles from Block Copolymer Blend Solution Construction”, Nature Communications, 2013, 4:2297, DOI: 10.1038/ncomms3297.
Lim, Y. H.; Heo, G. S.; Cho, S.; Wooley, K. L. “Construction of a Reactive Diblock Copolymer, Polyphosphoester-block-Poly(L-lactide), as a Versatile Framework for Functional Materials that are Capable of Full Degradation and Nanoscopic Assembly Formation”, ACS Macro Lett., 2013, 2(9), 785-789, DOI: 10.1021/mz400229m. PMCID: PMC3808001.
Gustafson, T. P.; Lonnecker, A. T.; Heo, G. S.; Zhang, S.; Dove, A. P.; Wooley, K. L. “Poly(d-glucose carbonate) Block Copolymers: A platform for natural product-based nanomaterials with solvothermatic characteristics”, Biomacromolecules, 2013, 14(9), 3346-3353, DOI: 10.1021/bm4010832.
Elsabahy, M.; Samarajeewa, S.; Raymond, J. E.; Clark, C.; Wooley, K. L. “Shell-crosslinked knedel-like nanoparticles induce lower immunotoxicity than their non-crosslinked analogs”, J. Mater. Chem. B, 2013, 1(39), 5241-5255, DOI: 10.1039/c3tb20668h. PMCID: PMC3811931.
Shen, Y.; Fang, H.; Zhang, K.; Shrestha, R.; Wooley, K. L.; Taylor, J.-S. A. “Efficient Protection and Transfection of siRNA by Cationic Shell Crosslinked Knedel-like Nanoparticles (cSCKs)”, Nucleic Acid Therapeutics, 2013, 23(2), 95-108, DOI: 10.1089/nat.2012.0390. PMCID: PMC3619153.
Wang, Z.; Zhang, K.; Shen, Y.; Smith, J.; Bloch, S.; Achilefu, S.; Wooley, K. L.; Taylor, J.-S. A. “Imaging mRNA Expression Levels in Living Cells with PNA DNA Binary FRET Probes Delivered by Cationic Shell Crosslinked Nanoparticles”, Organic and Biomolecular Chemistry, 2013, 11(19), 3159-3167, DOI: 10.1039/c3ob26923j. PMCID: PMC3619153.
Zhang, S.; Wang, H.; Shen, Y.; Zhang, F.; Seetho, K.; Zou, J.; Taylor, J.-S. A.; Dove, A. P.; Wooley, K. L. “A Simple and Efficient Synthesis of an Acid-labile Polyphosphoramidate by Organobase-catalyzed Ring-opening Polymerization and Transformation to Polyphosphoester Ionomers by Acid Treatment”, Macromolecules, 2013, 46(13), 5141-5149, DOI: 10.1021/ma400675m. PMCID: PMC3755629.
Lee, Y.-J. C.; Wu, B.; Raymond, J. E.; Zeng, Y.; Fang, X.; Wooley, K. L.; Liu, W. R. “A Genetically Encoded Acrylamide Functionality”, ACS Chem. Biol., 2013, 8(8), 1664-1670, DOI: 10.1021/cb400267m. PMCID: PMC3746000.
Shah, P. N.; Lin, L. Y.; Smolen, J. A.; Tagaev, J. A.; Gunsten, S. P.; Han, D. S.; Heo, G. S.; Li, Y.; Zhang, F.; Zhang, S.; Wright, B. D.; Panzner, M. J.; Youngs, W. J.; Brody, S. L.; Wooley, K. L.; Cannon, C. L. “Synthesis, Characterization, and in vivo Efficacy of Shell Crosslinked Nanoparticle Formulations Carrying Silver Antimicrobials as Aerosolized Therapeutics”, ACS Nano, 2013, 7(6), 4977-4987, DOI: 10.1021/nn400322f.
Mikami, K.; Lonnecker, A. T.; Gustafson, T. P.; Zinnel, N. F.; Pai, P.-J.; Russell, D. H.; Wooley, K. L. “Polycarbonates Derived from Glucose via an Organocatalytic Approach”, J. Am. Chem. Soc., 2013, 135(18), 6826-6829, DOI: 10.1021/ja402319m.
Zou, J.; Zhang, F.; Zhang, S.; Fan, J.; Raymond, J. E.; Zhu, J.; Li, A.; Seetho, K.; Pochan, D. J.; Wooley, K. L. “Responsive organogels formed by supramolecular self assembly of PEG-block-allyl-functionalized polypeptides into ß-sheet-driven polymeric ribbons”, Soft Matter, 2013, 9(25), 5951-5958, DOI: 10.1039/c3sm50582k.
Zou, J.; Fan, J.; He, X.; Zhang, S.; Wang, H.; Wooley, K. L. “A Facile Glovebox-free Strategy to Significantly Accelerate the Syntheses of Well-defined Polypeptides by N-Carboxyanhydride (NCA) Ring Opening Polymerizations”, Macromolecules, 2013, 46(10), 4223-4226, DOI: 10.1021/ma4007939. PMCID: PMC3686519.
Elsabahy, M.; Shrestha, R.; Taylor, S.; Leonard, J.; Wooley, K. L. “Multifunctional Hierarchically-assembled Nanostructures as Complex Stage-wise Dual-delivery Systems for Coincidental Yet Differential Trafficking of siRNA and Paclitaxel”, Nano Lett., 2013, 13(5), 2172-2181, DOI: 10.1021/nl4006645. PMCID: PMC3681414.
Elsabahy, M.; Wooley, K. L. “Cytokines as Biomarkers of Nanoparticle Immunotoxicity”, Chem. Soc. Rev., 2013, 42(12), 5552-5576, DOI: 10.1039/c3cs60064e. PMCID: PMC3665642.
Zhang, S.; Zou, J.; Elsabahy, M.; Karwa, A.; Li, A.; Moore, D. A.; Dorshow, R. B.; Wooley, K. L. “Poly(ethylene oxide)-block-polyphosphester-based Paclitaxel Conjugates as a Platform for Ultra-high Paclitaxel-loaded Multifunctional Nanoparticles”, Chem. Sci., 2013, 4, 2122-2126, DOI: 10.1039/c3sc50252j.
Shen, Y.; Shrestha, R.; Ibricevic, A.; Gunsten, S. P.; Welch, M. J.; Wooley, K. L.; Brody, S. L.; Taylor, J.-S. A.; Liu, Y. “Antisense PNA Functionalized Cationic Nanocomplex for in vivo mRNA Detection”, Interface Focus, 2013, 3, 20120059, DOI: 10.1098/rsfs.2012.0059. PMCID: PMC3638413.
Samarajeewa, S.; Ibricevic, A.; Gunsten, S. P.; Shrestha, R.; Elsabahy, M.; Brody, S. L.; Wooley, K. L. “Degradable Cationic Shell Crosslinked Knedel-like Nanoparticles: Synthesis, degradation, nucleic acid binding and in vitro evaluation”, Biomacromolecules, 2013, 14(4), 1018-1027, DOI: 10.1021/bm3018774. PMCID: PMC3640429.
Lee, Y.; Heo, G. S.; Zeng, H.; Wooley, K. L.; Hilty, C. “Detection of Living Anionic Species in Polymerization Reaction Using Hyperpolarized NMR”, J. Am. Chem. Soc., 2013, 135(12), 4636-4639, DOI: 10.1021/ja4001008.
Sun, G.; Cho, S.; Clark, C.; Verkhoturov, S.; Eller, M. J.; Li, A.; Pavia-Jiménez, A.; Schweikert, E. A.; Thackeray, J. W.; Trefonas, P.; Wooley, K. L. “Nanoscopic Cylindrical Dual Concentric and Lengthwise Block Brush Terpolymers as Covalent Pre-assembled High Resolution and High Sensitivity Negative-tone Photoresist Materials”, J. Am. Chem. Soc., 2013, 135(11), 4203-4206, DOI: 10.1021/ja3126382.
Zhang, F.; Elsabahy, M.; Zhang, S.; Lin, L. Y.; Zou, J.; Wooley, K. L. “Shell Crosslinked Knedel-like Nanoparticles for Delivery of Cisplatin: Effects of crosslinking”, Nanoscale, 2013, 5(8), 3220-3225, DOI: 10.1039/c3nr34320k.
Samarajeewa, S.; Shrestha, R.; Elsabahy, M.; Karwa, A.; Li, A.; Zentay, R. P.; Kostelc, J. G.; Dorshow, R. B.; Wooley, K. L. “In vitro Efficacy of Paclitaxel-loaded Dual-responsive Shell Crosslinked Polymer Nanoparticles Having Orthogonally-degradable Disulfide Crosslinked Corona and Polyester Core Domains”, Molecular Pharmaceutics, 2013, 10(3), 1092-1099, DOI: 10.1021/mp3005897.
Zhu, J.; Zhang, S.; Zhang, F.; Wooley, K. L.; Pochan, D. J. “Hierarchical Assembly of Complex Block Copolymer Nanoparticles into Multicompartment Superstructures through Tunable Interparticle Associations”, Adv. Func. Mater., 2013, 23(14), 1767-1773, DOI: 10.1002/adfm.201202323.

Patents

“Compositions Containing Sugar-based Bisphenol A Polycarbonate Analogs and Methods of Manufacture and Use Thereof”, Boopathi, Senthil K.; Jahnke, Ashlee A.; Wooley, Karen L.; U.S. Provisional Patent Application, No. 63/683,806, filed August 16, 2024.4, PCT International Application Serial No. PCT/US2025/042324, filed August 17, 2025.
“Polymer”, Boopathi, Senthil K.; Jahnke, Ashlee A.; Sun, Guorong; Taylor, Stephen John C.; Wooley, Karen L.; U.S. Provisional Patent Application Serial No. 63/509,979, filed June 23, 2023; U.S. NonProvisional Patent Application Serial No. 18/749,879, filed June 21, 2024; PCT International Application Serial No. PCT/US24/34925, filed June 21, 2024; WO 2024/263854 A1, December 26, 2024.
“Polymer”, Boopathi, Senthil K.; Jahnke, Ashlee A.; Sun, Guorong; Taylor, Stephen John C.; Wang, Hai.; Wooley, Karen L.; U.S. Provisional Patent Application Serial No. 63/509,994, filed June 23, 2023.; U.S. Non-Provisional Patent Application Serial No. 18/749,963, filed June 21, 2024; PCT International Application Serial No. PCT/US24/34940, filed June 21, 2024; WO 2024/263862 A1, December 26, 2024.
"Degradable Polycarbonate Sport Fishing Materials", Wooley, Karen L.; Felder, Simcha E.; Versaw, Brooke A.; Jahnke, Ashlee A.; Link, Lauren A.; Wooley, Mark W.; Hinton, Charles A.; Howell, Jr., William R.; U.S. Provisional Patent Application Serial No. 62/362,885, filed July 15, 2016; U.S. Patent Application Serial No. 15/650,244, filed July 14, 2017; PCT International Application Serial No. PCT/US2017/042061, filed July 14, 2017; US Patent Application Publication No. 20180016390-A1, filed January 18, 2018. Appl. No. EP3484942 filed May 22, 2019; U.S. Patent Number 10,329,381, issued June 25, 2019.
"Functional, Cross-Linked Nanostructures For Tandem Optical Imaging and Therapy", Neumann, William L.; Dorshow, Richard B., Freskos, John N.; Wooley, Karen L.; Lee, Nam S.; Lin, Lily Y.; Sun, Guorong; U.S. Patent Application Serial No. 13/697,149, filed November 17, 2011; WO 2011143524, filed November 17, 2011; PCT International Application Serial No. PCT/US2011/036392, filed December 13, 2012; Prior Publication Data: US 2013/0137976 A1, May 30, 2013; U.S. Patent Number 9,295,650, issued March 29, 2016, and U.S. Patent Number 9,662,387 B2, issued May 30, 2017.
"Ternary Antifouling Compositions and Methods", Wooley, Karen L.; Raymond, Jeffery E.; Pollack, Kevin A; Imbesi, Philip M; ; U.S. Patent Application Serial No. 14/575,625, filed December 18, 2014; WO 2013192529; Prior Publication Data: US 2015/0307720 A1, October 29, 2015; U.S. Patent Number 9,422,433 issued August 23, 2016.
"Self-Assembled Structures, Method of Manufacture Thereof and Articles Comprising The Same", Cho, Sangho; Sun, Guorong; Wooley, Karen L.; Thackeray, James W.; Trefonas, III, Peter; U.S. Patent Application Serial No. 14/020,371, filed September 6, 2013; Prior Publication Data: US 2015/0072292 A1, March 12, 2015; U.S. Patent Number 9,405,189 issued August 2, 2016.
"Self-Assembled Structures, Method of Manufacture Thereof and Articles Comprising The Same", Cho, Sangho; Sun, Guorong; Wooley, Karen L.; Thackeray, James W.; Trefonas, III, Peter; U.S. Patent Application Serial No. 14/020,343, filed September 6, 2013; Prior Publication Data: US 2015/0072291, filed March 12, 2015.
"Self-Assembled Structures, Method of Manufacture Thereof and Articles Comprising The Same", Cho, Sangho; Sun, Guorong; Wooley, Karen L.; Thackeray, James W.; Trefonas, III, Peter; U.S. Patent Application Serial No. 13/681,019, filed November 19, 2012; Prior Publication Data: US 2014/0141376 A1, May 22, 2014; U.S. Patent Number 8,822,130 issued September 2, 2014.
"Self-Assembled Structures, Method of Manufacture Thereof and Articles Comprising The Same", Cho, Sangho; Sun, Guorong; Wooley, Karen L.; Thackeray, James W.; Trefonas, III, Peter; U.S. Patent Application Serial No. 13/681,026, filed November 19, 2012; Prior Publication Data: US 2014/0141375 A1, May 22, 2014; U.S. Patent Number 9,223,214 issued December 29, 2015.
"Self-Assembled Structures, Method of Manufacture Thereof and Articles Comprising The Same", Cho, Sangho; Sun, Guorong; Wooley, Karen L.; Thackeray, James W.; Trefonas, III, Peter; Full Appl. Serial Number 13/681,012, filed November 19, 2012; Prior Publication Data: US 2014/0142252, May 22, 2014.
"Self-Assembled Structures, Method of Manufacture Thereof and Articles Comprising The Same", Cho, Sangho; Sun, Guorong; Wooley, Karen L.; Thackeray, James W.; Trefonas, III, Peter; U.S. Patent Application Serial No. 13/681,002, filed November 19, 2012; Prior Publication Data: US 2014/0142249 A1, May 22, 2014; U.S. Patent Number 9,447,220 issued September 20, 2016.
"Polymer-Drug Systems", Wooley, Karen L.; Zou, Jiong; El Sabahy, Mahmoud; Zhang, Shiyi; Zhang, Fuwu; U.S. Patent Number 9,545,447 issued January 17, 2017.
"Brush Copolymers", Cheng, Chong; Khoshdel, Ezat; Wooley, Karen L.; Patent WO 2008/064972, U.S. Patent Number 7,960,479 issued June 14, 2011.
"Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH", Wooley, Karen L.; Dorshow, Richard B.; Freskos, John N.; Neumann, William L.; Shieh, Jeng J.; Lee, Nam S.; Lin, Yun; Sun, Guorong; PCT Int. Appl. US2011/036411 Filed May 13, 2011; Int. Pub. No. WO 2011/143540 A1 Int. Pub. Date November 17, 2011. Based upon U.S. Provisional Appl. No. 61/334,723 Filed May 14, 2010. Published December 03, 2015. WO 2011/143540 A1.
"Degradable Polycarbonates", Wooley, Karen L; Besset, Celine J.; Lonnecker, Alexander T; Streff, Jennifer M.; Kristufek, Samantha L.; Hearon, Michael K.; New International (PCT) Patent PCT/US2011/056204; WO 2012/051448 A1; Filed October 13, 2011. Based on U.S. Provisional Appl. No. 61/392,893; filed October 13, 2010.
"Composition Comprising Brush Copolymer For Treating Hair", Burry, Jason Shaun; Cheng, Chong; Evans, Richard Livesey; Khoshdel, Ezat; Wooley, Karen Lynn; Patent WO 2008/064973; granted August 2010.
"Photonic Shell-Core Cross Linked and Functionalized Nanostructures for Biological Applications", Neumann, William L.; Rajagopalan, Raghavan; Dorshow, Richard B.; Shieh, J. J.; Wooley, Karen L.; Lee, Nam S.; Appl. Serial Number 60/986171; filed November 7, 2007.
"Dendritic-based Macromolecules", Fréchet, Jean M. J.; Hawker, Craig J.; Wooley, Karen L.; U.S. Patent Number 7,101,937 issued September 5, 2006.
"Cell-permeable Nanoconjugates of Shell-crosslinked Knedel (SCK) and Peptide Nucleic Acids ("PNAs") with uniquely expressed or over-expressed mRNA-targeting Sequences for Early Diagnosis and Therapy of Cancer", Becker, Matthew L.; Fang, Huafeng; Li, Xiaoxu; Pan, Dipanjan; Rossin, Raffaella; Sun, Xiankai; Taylor, John-Stephen; Turner, Jeffrey L.; Welch, Michael J.; Wooley, Karen L.; WO 2006044716; U.S. Patent Number 8,354,093 issued January 15, 2013.
"Particles Comprising Amphiphilic Copolymers, Having a Cross-linked Shell Domain and an Interior Core Domain, Useful for Pharmaceutical and Other Applications", Wooley, K. L.; Thurmond II, K. Bruce; Huang, Haiyong; WO 97/49387, U.S. Patent Number 6,383,500 issued May 7, 2002.
"Dendritic-based Macromolecules and Method of Production", Fréchet, Jean M. J.; Hawker, Craig J.; Wooley, Karen L.; Patent WO 9321259, US 92868535.

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